As the article explains, TADs are a newly discovered design feature of the genome that partition different groups of genes into neighborhoods. If these partitions are broken, various diseases may occur.
By conducting research on TADs, scientists hope to gain a more in depth understanding of how gene expression is controlled. Dr. Richard Young of the Whitehead Institute and his team are involved in TADs research and are continuing to push the boundaries of knowledge about genetic neighborhoods.
For more information, read the full article.